IRB Reliance Agreements

USC promotes and engages in agreements by which an IRB relies on the review conducted by another entity. These agreements vary in scope, terms, and terminology. These agreements are designed to reduce duplication and increases efficiency by designating a single IRB review when more than one site is involved in a research project. Among the commonly used reliance agreements are:

  • Memoranda of Understanding (MOU)
  • IRB Authorization Agreements (IRBAA)
  • Master Reliance Agreement (MRA)
  • Collaborative Review Agreement (CRA)

Agreements to which USC is a party: